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KMID : 1161420100130030640
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Journal of Medicinal Food
2010 Volume.13 No. 3 p.640 ~ p.649
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Dietary Ungerminated and Germinated Soybean Supplementation Improves Bone Mineralization and Strength in Growing Male Rats
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Hong Hee-Ok
Kim Woo-Jung
Yoo Sang-Ho
Abanto Oliver D.
Kim Tae-Jin
Kim Young-Jin
Jung Byung-Moon
Yun Sung-Seob
Hwang Seong-Gu
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Abstract
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It has been thought that soybean products rich in phytoestrogenic isoflavones are effective in promoting bone metabolism in ovariectomized rats. However, it is not clear if such an effect can be changed by germination of soybean and can be observed in growing males. The present study was undertaken to determine the effects of different concentrations of dietary ungerminated and germinated soybean (UGS and GS, respectively) on bone metabolism in young male rats. Forty-nine 6-week-old male Sprague-Dawley rats were assigned to seven dietary treatment groups: AIN 93G (control); control with UGS powder at 3% (UGS-L), 15% (UGS-M), or 30% (UGS-H); and control with GS powder at 3% (GS-L), 15% (GS-M), or 30% (GS-H). The biomarkers of bone metabolism (plasma and urinary Ca and P) and the physical properties and mineral content of bones were measured. Plasma osteocalcin and urinary deoxypyridinoline levels were not affected by soybean diets. The plasma P level was significantly elevated by dietary soybeans (P?
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KEYWORD
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bone mineral content, deoxypyridinoline, germinated soybean, osteocalcin
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